If this is a new deduction/benefit code and the Setup Payroll Parameters were run prior to the new deduction/benefit code setup, you will need to load the new code manually the first time. The code will then automatically load for future payrolls.
Payroll Processing Menu -> Setup Payroll Parameters (KE0159)
Note: If the deduction/benefit is not defined in the field outlined, it is not tagged and therefore will not be activated.